WP3 webinar - Identifying and addressing the operational challenges of pragmatic trials

6 October, 2016 

SPEAKERS

Rick Grobbee Professor of Clinical Epidemiology, University Medical Center Utrecht	Iris Goetz Research Advisor Epidemiology, Global Health Outcomes, Eli Lilly	Mira Zuidgeest Assistant Professor, University Medical Center Utrecht

GetReal aims to show how robust new methods of real-world evidence (RWE) collection and synthesis can be developed and considered for adoption earlier in pharmaceutical R&D and the healthcare decision making process. This will require companies, healthcare decision makers and other stakeholders to work together to generate a consensus on best practice in the use of RWE in regulatory and reimbursement decision-making.

Within work package 3 of GetReal we identified operational challenges when implementing pragmatic trials to investigate the effectiveness of medicines. We then proceeded to estimate the impact of these challenges on the ability to generate the RWE originally aimed for and the feasibility of the research. Lastly we provide guidance on how to design pragmatic trials while ensuring operational feasibility, most notably with a tool (development ongoing) guiding study teams through the design of a pragmatic trial. This webinar gives you an overview of all the above.